Mr. Guest was a boot and shoemaker who had a business on Blackfriars Road, on the Surrey side of the Thames. This coin, issued in 1795, reflects his profession as a wholesale manufacturer of ladies shoes and boots. Sometime later, Mr. Guest became a purveyor of of medicinal pills and lotions and author of the book Guestonian Medicines (1809), which sounds like its basically a written infomercial full of testimonials (some which are excerpted as printed in 1817 and 1816 issues of La Belle Assemblee).
He was later identified by lists as one of many “quacks” during the era.